I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). Also used as reactant in Grignard-reactions for the introduction of the n-propyl group.
Kenneth N. Campbell; James O. Knobloch; Barbara K. Campbell. The Preparation and Some Reactions of 1,1,1-Trifluoro-2-alkenes.J. Am. Chem. Soc.,1950, 72(10), 4380-4384.
Rima S. Al-awar; Sajan P. Joseph; Daniel L. Comins. Conversion of N-acyl-2,3-dihydro-4-pyridones to 4-chloro-1,2-dihydropyridines using the Vilsmeier Reagent. Synthesis of (-)-coniine and (±)-lupinine. J. Org. Chem., 1993, 58(27), 7732-7739.
Hazard Statements: H225-H261-H314-H318
Highly flammable liquid and vapour. In contact with water releases flammable gas. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P223-P210-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from any possible contact with water, because of violent reaction and possible flash fire. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.