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4-(4-Methyl-1-piperazinyl)benzeneboronic acid pinacol ester is used as pharmaceutical intermediate.
Stephen Brand; Neil R.Norcross; Stephen Thompson; Justin R.Harrison; Victoria C.Smith; David A.Robinson; Leah S.Torrie; Stuart P.McElroy; Irene Hallyburton; Suzanne Norval; Paul Scullion; Laste Stojanovski; Frederick R.C.Simeons; Daan van Aalten; Julie A.Frearson; Ruth Brenk; Alan H.Fairlamb; Michael A.J.Ferguson; Paul G.Wyatt; Ian H.Gilbert; Kevin D.Read. Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-Myristoyltransferase inhibitors: Identification and evaluation of CNS penetrant compounds as potential treatments for Stage 2 Human African Trypanosomiasis. J. Med. Chem. 2014, 57, (23),9855-9869