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H51729 (S)-(-)-3-(Boc-amino)pyrrolidine, 98%

CAS Number
122536-76-9
Synonyms
(S)-3-(tert-Butoxycarbonylamino)pyrrolidine

Stock No. Size Price ($) Quantity Availability
H51729-06 5g 93.20
H51729-14 25g 365.00
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(S)-(-)-3-(Boc-amino)pyrrolidine, 98%

MDL
MFCD00143194

Chemical Properties

Formula
C9H18N2O2
Formula Weight
186.25
Melting point
50-54°
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Soluble in water.

Applications

(S)-(-)-3-(Boc-amino)pyrrolidine is used as pharmaceutical intermediate.

Notes

Air sensitive. Incompatible with oxidizing agents and carbon dioxide.

Literature References

Kyoji Tomita; Yasunori Tsuzuki; Koh-ichiro Shibamori; Masanori Tashima; Fumie Kajikawa; Yuji Sato; Shigeki Kashimoto; Katsumi Chiba; Katsuhiko Hino. Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1. J. Med. Chem. 2002, 45, (25), 5564-5575

 

Masayuki Iwakubo; Atsuya Takami; Yuji Okada; Takehisa Kawata; Yoshimichi Tagami; Motoko Sato; Terumi Sugiyama; Kayoko Fukushima; Shinichiro Taya; Mutsuki Amano; Kozo Kaibuchi; Hiroshi Iijima. Design and synthesis of rho kinase inhibitors (III). Bioorganic & Medicinal Chemistry. 2007, 15, (2),1022-1033

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
5377813
Harmonized Tariff Code
2933.99
TSCA
No

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