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It is employed in the design, synthesis, and biological evaluation of novel nonsteroidal farnesoid x receptor (fxr) antagonists.
Dr. Rachel A. Barnard, et al. Two-Dimensional Crystals from Reduced Symmetry Analogues of Trimesic Acid.Chem. Eur. J.,2015,21(15), 5954-5961.
Huang Huang, et al. Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal Farnesoid X Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism.ChemMedChem.,2015,10(7), 1184-1199.