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143900-43-0 - (R)-1-Boc-3-hydroxypiperidine, 97% - H52556 - Alfa Aesar

H52556 (R)-1-Boc-3-hydroxypiperidine, 97%

CAS Number

Size Price ($) Quantity Availability
1g 46.50
5g 187.00
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(R)-1-Boc-3-hydroxypiperidine, 97%


Chemical Properties

Formula Weight
Melting point
Flash Point


(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.


Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Literature References

Christophe Benard; Rahim Mohammad; Neerja Saraswat; Rudong Shan; Samarendra N.Maiti; Peter G.M.Wuts; Michael Stier; Teresa Lints; James Bradow; Jacob B.Schwarz. Convenient preparation of optically pure 3-aryloxy-pyrrolidines. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 2008, 38, (4),517-524


Nora Liu; Sascha Hoogendoorn; Bas van de Kar; Allard Kaptein; Tjeerd Barf; Christoph Driessen; Dmitri V.Filippov; Gijsbert A. van der Marel; Mario van der Stelt; Herman S.Overkleeft. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org. Biomol. Chem. 2015, 13, (18),5147-5157

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • B21674

    Safranine O
  • H26321

    3-Chloro-5-(trifluoromethyl)phenol, 97%
  • H27428

    Tricyclohexylphosphonium tetrafluoroborate, 99%
  • H32579

    3-Chloro-5-(trifluoromethoxy)phenol, 97%
  • H52771

    (S)-1-Boc-3-hydroxypiperidine, 97%

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