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H52743 (R)-3-Hydroxypyrrolidine hydrochloride, 97%

CAS Number
104706-47-0
Synonyms
(R)-3-Pyrrolidinol hydrochloride

Stock No. Size Price ($) Quantity Availability
H52743-03 1g 21.80
H52743-06 5g 86.70
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(R)-3-Hydroxypyrrolidine hydrochloride, 97%

MDL
MFCD00191570

Chemical Properties

Formula
C4H9NO•HCl
Formula Weight
123.58
Melting point
104-107°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in DMSO.

Applications

(R)-3-Hydroxypyrrolidine hydrochloride is used as a darifenacin Intermediate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

Z Li.; HJ Feiten.; JB van Beilen.; W Duetz. Preparation of optically active N-benzyl-3-hydroxypyrrolidine by enzymatic hydroxylation. Tetrahedron: Asymmetry. 199910 (7), 1323-1333.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
4450078
Harmonized Tariff Code
2933.99
TSCA
No

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