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H52784 (±)-1-Boc-3-(hydroxymethyl)piperidine, 97%

CAS Number
116574-71-1
Synonyms
1-Boc-3-piperidinemethanol

Stock No. Size Price ($) Quantity Availability
H52784-06 5g 78.10
H52784-14 25g 307.00
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(±)-1-Boc-3-(hydroxymethyl)piperidine, 97%

MDL
MFCD03094733

Chemical Properties

Formula
C11H21NO3
Formula Weight
215.29
Melting point
77-81°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in methanol and dimethylformamide(DMF).

Applications

(+/-)-1-Boc-3-(hydroxymethyl)piperidine is used as a reactant for synthesis of Pim-1 inhibitors, Vasopressin1b receptor antagonists, CXCR4 antagonists as anti-HIV agents, Amide CCR5 antagonist, PSSRI-based inhibitors of S. aureus multidrug efflux pumps and Human GnRH receptor antagonists.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Peter Beak; Won Koo Lee. .alpha.-Lithioamine synthetic equivalents: syntheses of diastereoisomers from Boc derivatives of cyclic amines. J. Org. Chem. 1993, 58, (5),1109-1117

 

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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