I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1-Boc-piperidine-4-carboxaldehyde is used as reactant for synthesis of Pim-1 inhibitors, selective GPR119 agonists for type II diabetes, M-tropic (R5) HIV-1 replication inhibitors, HDAC inhibitors and selective 5-HT6 antagonists. It is also used as reactant for three-component vinylogous Mannich reactions
Yibin Xiang; Bradford Hirth; Gary Asmussen; Hans-Peter Biemann; Kimberly A.Bishop; Andrew Good; Maria Fitzgerald; Tatiana Gladysheva; Annuradha Jain; Katherine Jancsics; Jinyu Liu; Markus Metz; Andrew Papoulis; Renato Skerlj; J.David Stepp; Ronnie R.Wei. The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2011, 21, (10),3050-3056
Jason W.Szewczyk; John Acton; Alan D.Adams; Gary Chicchi; Stanley Freeman; Andrew D.Howard; Yong Huang; Cai Li; Peter T.Meinke; Ralph Mosely; Elizabeth Murphy; Rachel Samuel; Conrad Santini; Meng Yang; Yong Zhang; Kake Zhao; Harold B.Wood. Design of potent and selective GPR119 agonists for type II diabetes. Bioorganic & Medicinal Chemistry Letters. 2011, 21, (9),2665-2669
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.