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850567-97-4 - 2-(Methylsulfinyl)benzeneboronic acid, 97% - 2-(Methanesulfinyl)phenylboronic acid, 97% - H53209 - Alfa Aesar

H53209 2-(Methylsulfinyl)benzeneboronic acid, 97%

CAS Number
850567-97-4
Synonyms
2-(Methanesulfinyl)phenylboronic acid, 97%

Size Price ($) Quantity Availability
250mg 111.00
1g 352.00
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2-(Methylsulfinyl)benzeneboronic acid, 97%

MDL
MFCD03095261

Chemical Properties

Formula
C7H9BO3S
Formula Weight
184.02
Melting point
118-122°
Solubility
Slightly soluble in water.

Applications

It is a useful intermediate in pharmaceutical intermediate. Boronic Acids are important chemical building blocks employed in cross coupling reactions. The ability of boronic acids to reversibly bind diol functional groups has been utilized for fluorescent detection of saccharides. The compound Bortezomib utilizes the boronic acid for its proteasome inhibitory effect.

Notes

Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.

Literature References

Virgil Percec.; Jin-Young Bae.; Dale H. Hill. Aryl Mesylates in Metal Catalyzed Homocoupling and Cross-Coupling Reactions. 2. Suzuki-Type Nickel-Catalyzed Cross-Coupling of Aryl Arenesulfonates and Aryl Mesylates with Arylboronic Acids.J. Org. Chem. 1995, 60 (4),1060-1065 .

Manfred Baumgarth.; Norbert Beier.; Rolf Gericke. (2-Methyl-5-(methylsulfonyl)benzoyl)guanidine Na+/H+ Antiporter Inhibitors.J. Med. Chem. 1997, 40 (13),2017-2034 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2931.90
TSCA
No

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