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197958-29-5 - Pyridine-2-boronic acid, 95% - H53314 - Alfa Aesar

H53314 Pyridine-2-boronic acid, 95%

CAS Number
197958-29-5
Synonyms

Size Price ($) Quantity Availability
250mg 170.98
1g 551.05
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Pyridine-2-boronic acid, 95%

MDL
MFCD00151844

Chemical Properties

Formula
C5H6BNO2
Formula Weight
122.92
Melting point
>300°

Applications

Pyridine-2-boronic acid is used as a key starting material for the formation of pyridyl boronic ester such as pyridine-2-boronic acid dimethyl ester. Furthermore, the dimethyl ester reacts with bromquinoline to prepare the 2-pyridyl derivative of quinoline.

Notes

Incompatible with strong oxidizing agents.

Literature References

Sreedhar, B.; Yada, D.; Reddy, P. S. Nanocrystalline Titania-Supported Palladium (0) Nanoparticles for Suzuki-Miyaura Cross-Coupling of Aryl and Heteroaryl Halides. Adv. Synth. Catal. 2011, 353 (14-15), 2823-2836.

Chen, K.; Peterson, R.; Math, S. K.; LaMunyon, J. B.; Testa, C. A.; Cefalo, D. R. Lithium trihydroxy/triisopropoxy-2-pyridylborate salts (LTBS): synthesis, isolation, and use in modified Suzuki-Miyaura cross-coupling reactions. Tetrahedron Lett. 2012, 53 (36), 4873-4876.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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