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1501-84-4 - 1-(1-Adamantyl)ethylamine hydrochloride, 99% - Rimantadine hydrochloride - H53377 - Alfa Aesar

H53377 1-(1-Adamantyl)ethylamine hydrochloride, 99%

CAS Number
1501-84-4
Synonyms
Rimantadine hydrochloride

Size Price ($) Quantity Availability
5g 59.00
25g 236.00
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1-(1-Adamantyl)ethylamine hydrochloride, 99%

MDL
MFCD00072023

Chemical Properties

Formula
C12H21N•HCl
Formula Weight
215.77
Melting point
375°
Solubility
Freely soluble in water.

Applications

1-(1-Adamantyl)ethylamine hydrochloride is indicated for the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults (17 years and older).

Notes

Stable under recommended storage conditions. Store away from oxidizing agents.

Literature References

Sander A.A.Kooijmans; Danielle Senyschyn; Muguntha M.Mezhiselvam; Julia Morizzi; Susan A.Charman; Babette Weksler; Ignacio-Andres Romero; Pierre-Olivier Couraud; Joseph A.Nicolazzo. The involvement of a Na?- and Cl?-dependent transporter in the brain uptake of amantadine and rimantadine. Molecular Pharmaceutics. 2012, 9, (4),883-893

 

Jonathan Hsu; Nancy Santesso; Reem Mustafa; Jan Brozek; Yao Long Chen; Jessica P.Hopkins; Adrienne Cheung; Gayane Hovhannisyan; Liudmila Ivanova; Signe A.Flottorp; Ingvil Saeterdal; Arthur D.Wong; Jinhui Tian; Timothy M.Uyeki; Elie A.Akl; Pablo Alonso-Coello; Fiona Smaill; Holger J.Schunemann. Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies. Annals of Internal Medicine. 2012, 156, (7),512-524

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8224
Harmonized Tariff Code
2921.30
TSCA
No
RTECS
AU4717000

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