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40365-61-5 - 2-(3-Butynyloxy)tetrahydropyran, 98% - H53385 - Alfa Aesar

H53385 2-(3-Butynyloxy)tetrahydropyran, 98%

CAS Number
40365-61-5
Synonyms

Size Price ($) Quantity Availability
5g 61.60
25g 246.00
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2-(3-Butynyloxy)tetrahydropyran, 98%

MDL
MFCD00012352

Chemical Properties

Formula
C9H14O2
Formula Weight
154.21
Boiling Point
92-95°/18mm
Flash Point
73°(163°F)
Density
0.984
Refractive Index
1.457

Applications

2-(3-Butynyloxy)tetrahydropyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. It is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.

Notes

Stable under recommended storage conditions. Store away from oxidizing agents.

Literature References

Christian Milo; Werner Grosch. Changes in the odorants of boiled trout (Salmo fario) as affected by the storage of the raw material. J. Agric. Food Chem. 1993, 41, (11),2076-2081

 

Yasunobu Sakoda; Kenji Matsui; Tadahiko Kajiwara; Akikazu Hatanaka. Chemical structure-odor correlation in a series of synthetic n-nonen-1-ols. Zeitschrift fur Naturforschung C. 1995, 50, (11-12),757-765

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H332-H315-H319-H335-H227

Toxic if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Precautionary Statements: P210-P261-P280-P301+P310-P305+P351+P338-P361-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2932.99
TSCA
No

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