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H53385 2-(3-Butynyloxy)tetrahydropyran, 98%

CAS Number
40365-61-5
Synonyms

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Bulk/Specialty

2-(3-Butynyloxy)tetrahydropyran, 98%

MDL
MFCD00012352

Chemical Properties

Formula
C9H14O2
Formula Weight
154.21
Boiling Point
92-95°/18mm
Flash Point
73°(163°F)
Density
0.984
Refractive Index
1.457
Storage & Sensitivity
Ambient temperatures.

Applications

2-(3-Butynyloxy)tetrahydropyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. It is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.

Notes

Stable under recommended storage conditions. Store away from oxidizing agents.

Literature References

Christian Milo; Werner Grosch. Changes in the odorants of boiled trout (Salmo fario) as affected by the storage of the raw material. J. Agric. Food Chem. 1993, 41, (11),2076-2081

 

Yasunobu Sakoda; Kenji Matsui; Tadahiko Kajiwara; Akikazu Hatanaka. Chemical structure-odor correlation in a series of synthetic n-nonen-1-ols. Zeitschrift fur Naturforschung C. 1995, 50, (11-12),757-765

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H302-H312-H315-H319-H332-H335

Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P210-P235-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2932.99
TSCA
No

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