Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

89343-06-6 - Triisopropylsilylacetylene, 97% - Ethynyltriisopropylsilane - H53405 - Alfa Aesar

H53405 Triisopropylsilylacetylene, 97%

CAS Number
89343-06-6
Synonyms
Ethynyltriisopropylsilane

Size Price ($) Quantity Availability
5g 55.00
25g 219.00
Add to Cart Add to Quote Request View Item

Triisopropylsilylacetylene, 97%

MDL
MFCD00075452

Chemical Properties

Formula
C11H22Si
Formula Weight
182.38
Boiling Point
50-52°/0.6mm
Flash Point
56°(133°F)
Density
0.813
Refractive Index
1.4527
Solubility
Miscible with organic solvents.

Applications

Triisopropylsilylacetylene is used as a reagent for the rhodium-catalyzed asymmetric alkylation of alpha, beta-unsaturated carbonyl compounds as well as in the synthesis of beta-alkynylated nitroalkanes. It is utilized in the preparation of bromoethynyl-triisopropyl-silane in the presence of the reagents such as N-bromo succinimide and silver nitrate. It is actively in involved in Sonogashira coupling reaction with 1-bromo-3-iodo-5-tertbutylbenzene.

Notes

Incompatible with strong acids, strong bases and strong oxidizing agents.

Literature References

Sawano, T.; Ashouri, A.; Nishimura, T.; Hayashi, T. Cobalt-Catalyzed Asymmetric 1, 6-Addition of (Triisopropylsilyl)-acetylene to alfa, beta, gamma, delta-Unsaturated Carbonyl Compounds. J. Am. Chem. Soc. 2012, 134 (46), 18936-18939.

Li, Y.; Liu, L.; Kong, D.; Wang, D.; Feng, W.; Yue, T.; Li, C. Palladium-Catalyzed Alkynylation of Morita-Baylis-Hillman Carbonates with (Triisopropylsilyl)acetylene on Water. J. Org. Chem. 2015, 80 (12), 6283-6290.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H315-H319-H335

Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3536241
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2931.90
TSCA
No

Recommended

  • A10221

    Imidazole, 99%
  • A10588

    Tetra-n-butylammonium fluoride, 1M soln. in THF
  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • L06374

    Trifluoroacetic acid, 99%
  • H55205

    Tetra-n-butylammonium dichromate, 99%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware