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Ethyl dimethylpyruvate is used as an allyl halide reactant in the presence of indium to release hydroxy unsaturated carbonyl compounds. It was also used in the synthesis of (2SR,4SR)-5(S)-(N-Boc)-amino-6-cyclohexyl-4-hydoxy-2-isopropyl hexanoic acid.
Alan R.Healy; Dr. Miho Izumikawa; Prof. Alexandra M.Z.Slawin; Dr. Kazuo Shin-ya; Prof. Nicholas J.Westwood. Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis . Angewandte Chemie International Edition. 2015, 54, (13),4046-4050
Hazard Statements: H226
Flammable liquid and vapour.
Precautionary Statements: P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Dispose of contents/container in accordance with local/regional/national/international regulations.