Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

38002-45-8 - 3-Bromo-1-trimethylsilyl-1-propyne, 98% - 3-(Trimethylsilyl)propargyl bromide - H53451 - Alfa Aesar

H53451 3-Bromo-1-trimethylsilyl-1-propyne, 98%

CAS Number
38002-45-8
Synonyms
3-(Trimethylsilyl)propargyl bromide

Size Price ($) Quantity Availability
5g 70.60
25g 280.00
Add to Cart Add to Quote Request View Item

3-Bromo-1-trimethylsilyl-1-propyne, 98%

MDL
MFCD00134460

Chemical Properties

Formula
C6H11BrSi
Formula Weight
191.14
Boiling Point
44-45°/2mm
Flash Point
63°(145°F)
Density
1.17
Refractive Index
1.483
Solubility
Immiscible with water.

Applications

3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Literature References

Wanat, P.; Walczak, S.; Wojtczak, B. A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Org. Lett. 2015, 17 (12), 3062-3065.

Guo, T.; Liu, Y.; Li, B.; Liu, H. Convenient synthesis of α,α-(bisallyl and bispropargyl)-substituted amines via aza-Barbier-type reaction. Tetrahedron Lett. 2015, 56 (19), 2469-2471.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319-H335

Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2037650
Harmonized Tariff Code
2931.90
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware