4-pyridylacetylene hydrochloride is used in the preparation of alkynyl platinum(II) compounds with dichloro (1,2-bis(diphenylphosphino)ethane)platinium(II) complex in the presence of base and copper iodide as catalyst. It is used as an intermediate in the synthesis of 1,4-bis(4-pyridyl)butadiyne.
Mishra, A.; Ravikumar, S.; Song, Y. H.; Prabhu, N. S.; Kim, H.; Hong, S. H.; Cheon, S.; Noh, J.; Chi, K. W. A new arene-Ru based supramolecular coordination complex for efficient binding and selective sensing of green fluorescent protein. Dalton Trans. 2014, 43 (16), 6032-6040.
Alvarino, C.; Simond, D.; Lorente, P. M.; Besnard, C.; Williams, A. F. Chains, Necklaces and Weaving Chain-link Grids from Self-Assembly Reactions. Chem. Eur. J. 2015, 21 (24), 8851-8858.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.