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4-pyridylacetylene hydrochloride is used in the preparation of alkynyl platinum(II) compounds with dichloro (1,2-bis(diphenylphosphino)ethane)platinium(II) complex in the presence of base and copper iodide as catalyst. It is used as an intermediate in the synthesis of 1,4-bis(4-pyridyl)butadiyne.
Mishra, A.; Ravikumar, S.; Song, Y. H.; Prabhu, N. S.; Kim, H.; Hong, S. H.; Cheon, S.; Noh, J.; Chi, K. W. A new arene-Ru based supramolecular coordination complex for efficient binding and selective sensing of green fluorescent protein. Dalton Trans. 2014, 43 (16), 6032-6040.
Alvarino, C.; Simond, D.; Lorente, P. M.; Besnard, C.; Williams, A. F. Chains, Necklaces and Weaving Chain-link Grids from Self-Assembly Reactions. Chem. Eur. J. 2015, 21 (24), 8851-8858.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant