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265651-18-1 - O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+% - N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate - HSTU - H54035 - Alfa Aesar

H54035 O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%

CAS Number
265651-18-1
Synonyms
N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate
HSTU

Size Price ($) Quantity Availability
1g 40.40
5g 161.00
25g 632.00
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O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%

MDL
MFCD01863753

Chemical Properties

Formula
C9H16F6N3O3P
Formula Weight
359.21
Melting point
ca 220° dec.
Sensitivity
Moisture Sensitive
Solubility
Soluble in acetonitrile 0.5 g/mL.

Applications

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

Notes

Moisture sensitive. Store under inert gas. Store away from oxidizing agents, water/ moisture.

Literature References

H J Gruber; G Kada; B Pragl; C Riener; C D Hahn; G S Harms; W Ahrer; T G Dax; K Hohenthanner; H G Knaus. Preparation of thiol-reactive Cy5 derivatives from commercial Cy5 succinimidyl ester. Bioconjugate Chemistry. 2000, 11 (2), 161-166.

Sjoerd Hak; Honorius M H F Sanders; Prashant Agrawal; Sander Langereis; Holger Grüll; Henk M Keizer; Francesca Arena; Enzo Terreno; Gustav J Strijkers; Klaas Nicolay. A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging. European Journal of Pharmaceutics and Biopharmaceutics. 2009, 72 (2), 397-404.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2925.19
TSCA
No

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