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265651-18-1 - O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+% - N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate - HSTU - H54035 - Alfa Aesar

H54035 O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%

CAS Number
N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate

Size Price ($) Quantity Availability
1g 36.72
5g 146.70
25g 560.41
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O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%


Chemical Properties

Formula Weight
Melting point
ca 220° dec.
Moisture Sensitive
Soluble in acetonitrile 0.5 g/mL.


Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.


Moisture sensitive. Store under inert gas. Store away from oxidizing agents, water/ moisture.

Literature References

H J Gruber; G Kada; B Pragl; C Riener; C D Hahn; G S Harms; W Ahrer; T G Dax; K Hohenthanner; H G Knaus. Preparation of thiol-reactive Cy5 derivatives from commercial Cy5 succinimidyl ester. Bioconjugate Chemistry. 2000, 11 (2), 161-166.

Sjoerd Hak; Honorius M H F Sanders; Prashant Agrawal; Sander Langereis; Holger Grüll; Henk M Keizer; Francesca Arena; Enzo Terreno; Gustav J Strijkers; Klaas Nicolay. A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging. European Journal of Pharmaceutics and Biopharmaceutics. 2009, 72 (2), 397-404.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


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