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N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine is used as pharmaceutical intermediate.
Jonathan B. Baell; Peter J. Duggan; Stewart A. Forsyth; Richard J. Lewise, Y. Phei Lok; Christina I. Schroeder; Nicholas E. Shepherd. Synthesis and biological evaluation of anthranilamide-based non-peptide mimetics of ω-conotoxin GVIA. Tetrahedron. 2006, 62 (31), 7284-7292.
Masood Hosseini; Longguang Jiang; Hans Peter Sørensen; Jan K. Jensen; Anni Christensen; Sarah Fogh; Cai Yuan; Lisbeth M. Andersen; Mingdong Huang; Peter A. Andreasen and Knud J. Jensen. Elucidation of the Contribution of Active Site and Exosite Interactions to Affinity and Specificity of Peptidylic Serine Protease Inhibitors Using Non-Natural Arginine Analogs. Molecular Pharmacology. 2009, 80 (4), 585-597.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant