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H54092 N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine, 98+%

CAS Number
152120-55-3
Synonyms
N,N'-Bis-Z-1-guanylpyrazole

Stock No. Size Price ($) Quantity Availability
H54092-03 1g 71.60
H54092-06 5g 279.00
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N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine, 98+%

MDL
MFCD02683516

Chemical Properties

Formula
C20H18N4O4
Formula Weight
378.38
Melting point
87-91°
Storage & Sensitivity
Ambient temperatures.

Applications

N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine is used as pharmaceutical intermediate.

Notes

Store in a cool, dry place, in a well sealed container. Store away from oxidizing agents.

Literature References

Jonathan B. Baell; Peter J. Duggan; Stewart A. Forsyth; Richard J. Lewise, Y. Phei Lok; Christina I. Schroeder; Nicholas E. Shepherd. Synthesis and biological evaluation of anthranilamide-based non-peptide mimetics of ω-conotoxin GVIA. Tetrahedron. 2006, 62 (31), 7284-7292.

Masood Hosseini; Longguang Jiang; Hans Peter Sørensen; Jan K. Jensen; Anni Christensen; Sarah Fogh; Cai Yuan; Lisbeth M. Andersen; Mingdong Huang; Peter A. Andreasen and Knud J. Jensen. Elucidation of the Contribution of Active Site and Exosite Interactions to Affinity and Specificity of Peptidylic Serine Protease Inhibitors Using Non-Natural Arginine Analogs. Molecular Pharmacology. 2009, 80 (4), 585-597.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.19
TSCA
No

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