1,3-Dioxane has been employed as solvent in the synthesis of 8- and 9-membered dioxazocines and dioxazonines.
Florian Medina; Céline Besnard; Jérôme Lacour. One-step synthesis of nitrogen-containing medium-sized rings via α-imino diazo intermediates. Organic Letters. 2015, 16 (12), 3232-3235.
Fabio Marchetti; Guido Pampaloni; Stefano Zacchini. The reactivity of molybdenum pentachloride with ethers: routes to the synthesis of Mo(IV)Cl4 adducts, Mo(V) chlorido-alkoxides and Mo(V) oxydo-chlorides. Dalton Transactions (Print Edition). 2013, 42 (42), 15226-15234.
Hazard Statements: H225-H315-H319-H335
Highly flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.