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4-(4-Methyl-1-piperazinylmethyl)benzoic acid is used as Imatinib intermediate, as pharmaceutical intermediate.
Elena V. Koroleva; Aleksey P. Kadutskii; Alexander V. Farina; Janna V. Ignatovich; Anastasiya L. Ermolinskaya; Klaudiya N. Gusak; Elena N. Kalinichenko. A practical synthesis of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acidthe key precursor toward imatinib. Tetrahedron Letters. 2012, 53 (38), 5056-5058.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.