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106261-48-7 - 4-(4-Methyl-1-piperazinylmethyl)benzoic acid, 97% - H54120 - Alfa Aesar

H54120 4-(4-Methyl-1-piperazinylmethyl)benzoic acid, 97%

CAS Number
106261-48-7
Synonyms

Size Price ($) Quantity Availability
250mg 51.50
1g 120.00
5g 600.00
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4-(4-Methyl-1-piperazinylmethyl)benzoic acid, 97%

MDL
MFCD01632530

Chemical Properties

Formula
C13H18N2O2
Formula Weight
234.30
Solubility
Slightly soluble in water.

Applications

4-(4-Methyl-1-piperazinylmethyl)benzoic acid is used as Imatinib intermediate, as pharmaceutical intermediate.

Notes

Store in a cool, dry place, in a well sealed container. Store away from oxidizing agents, acids, bases.

Literature References

Elena V. Koroleva; Aleksey P. Kadutskii; Alexander V. Farina; Janna V. Ignatovich; Anastasiya L. Ermolinskaya; Klaudiya N. Gusak; Elena N. Kalinichenko. A practical synthesis of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid—the key precursor toward imatinib. Tetrahedron Letters. 2012, 53 (38), 5056-5058.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.59
TSCA
No

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