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55314-16-4 - 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97% - H54187 - Alfa Aesar

H54187 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97%

CAS Number
55314-16-4
Synonyms

Size Price ($) Quantity Availability
250mg 19.60
1g 58.80
5g 235.00
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3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97%

MDL
MFCD00115180

Chemical Properties

Formula
C10H12N2O
Formula Weight
176.22
Solubility
Soluble in chloroform and dichloromethane.

Applications

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is used ads pharmaceutical intermediate, an imatinib intermediate.

Notes

Store in a cool, dry place, in a well sealed container. Store away from oxidizing agents, acids bases.

Literature References

Jürg Zimmermann; Elisabeth Buchdunger; Helmut Mett; Thomas Meyer; Nicholas B. Lydon; Peter Traxler. Phenylamino-pyrimidine (PAP) — derivatives: a new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors. Bioorganic & Medicinal Chemistry Letters. 1996, 6 (11), 1221-1226.

Rao, R Janaki Rama; S, A K; Rao, Bhujanga; Swapna, K; Rani, B Baby Rani; and Y.L.N. Murthy. Synthesis and Antimicrobial Activity of Novel 7-(Heteroaryl)-1,2,4-triazolo[1,5-a]-pyrimidine Derivatives. Asian Journal of Chemistry. 2012, 24 (4),1837-1843.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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