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944401-57-4 - 2-Amino-4-(trifluoromethyl)pyridine-5-boronic acid pinacol ester, 95% - 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridin-2-amine - H54372 - Alfa Aesar

H54372 2-Amino-4-(trifluoromethyl)pyridine-5-boronic acid pinacol ester, 95%

CAS Number
944401-57-4
Synonyms
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridin-2-amine

Size Price ($) Quantity Availability
250mg 164.80
1g 494.40
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2-Amino-4-(trifluoromethyl)pyridine-5-boronic acid pinacol ester, 95%

MDL
MFCD12923420

Chemical Properties

Formula
C12H16BF3N2O2
Formula Weight
288.07
Solubility
Slightly soluble in water.

Applications

2-Amino-4-(trifluoromethyl)pyridine-5-boronic acid pinacol ester is used as pharmaceutical intermediate.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Romeo Romagnoli; Pier Giovanni Baraldi; Maria Dora Carrion; Olga Cruz-Lopez; Carlota Lopez Cara; Giulia Saponaro; Delia Preti; Mojgan Aghazadeh Tabrizi; Stefania Baraldi; Allan R.Moorman; Fabrizio Vincenzi; Pier Andrea Borea; Katia Varani. Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor. Bioorganic & Medicinal Chemistry. 2014, 22, (1),148-166

 

GHS Hazard and Precautionary Statements

Hazard Statements: H319

Causes serious eye irritation.

Precautionary Statements: P280-P264-P305+P351+P338-P337+P313

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.

Other References

Beilstein
15519102
Harmonized Tariff Code
2934.99
TSCA
No

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