Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

H54378 (7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+%

CAS Number

Stock No. Size Price ($) Quantity Availability
H54378-03 1g 65.00
H54378-06 5g 256.00
Add to Cart Bulk/Specialty Print Quote View Item

(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+%


Chemical Properties

Formula Weight
Melting point
Storage & Sensitivity
Ambient temperatures.
Soluble in water.


(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate is used as reagent for synthesis of cyclic RGC pentapeptides for functionalization through click chemistry, fluorescent glucose bioprobes and ReactIR™ flow cell. It is also used as reagent for disulfide bond engineering, heteroaryl ether synthesis and optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.


Stable under recommended storage conditions. Store away from oxidizing agents.

Literature References

Hyang Yeon Lee; Jae Jeong Lee; Jongmin Park; Seung Bum Park. Development of fluorescent glucose bioprobes and their application on real-time and quantitative monitoring of glucose uptake in living cells. Chemistry: A European Journal. 2011, 17, (1),143-150


Markus Muttenthaler; Asa Andersson; Aline D de Araujo; Zoltan Dekan; Richard J.Lewis; Paul F.Alewood. Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of medicinal and pharmaceutical chemistry. 2010, 53, (24),8585-8596

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • 15789

    Oxalacetic acid, 98+%
  • H62744

    cis-3-(Boc-amino)cyclohexanemethanol, 97%
  • L11460

    2-Fluoro-4-(trifluoromethyl)benzophenone, 97%
  • A12676

    2-Methylstyrene, 98%, stab. with 0.1% 4-tert-butylcatechol
  • 42481

    Copper Beryllium rod, alloy C17200, 4.76mm (0.188in) dia

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware