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It is used as a pharmaceutical intermediate.
Xiaoqing Lv.; Huazhou Ying.; Xiaodong Ma.; Ni Qiu.; Peng Wu.; Bo Yang.; Yongzhou Hu. Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors. Eur. J. Med. Chem. 2015, 99 (24),36-50.
Timothy D. White.; Charles A. Alt.; Kevin P. Cole.; Jennifer McClary Groh.; Martin D. Johnson.; Richard D. Miller. How to Convert a Walk-in Hood into a Manufacturing Facility: Demonstration of a Continuous, High-Temperature Cyclization to Process Solids in Flow.Org. Process Res. Dev. 2014, 18 (11),1482-1491.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.