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5305-40-8 - 4,6-Dichloropyrimidine-5-carboxaldehyde, 97% - H54449 - Alfa Aesar

H54449 4,6-Dichloropyrimidine-5-carboxaldehyde, 97%

CAS Number

Size Price ($) Quantity Availability
1g 33.30
5g 125.00
25g 500.00
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4,6-Dichloropyrimidine-5-carboxaldehyde, 97%


Chemical Properties

Formula Weight
Melting point


4,6-Dichloropyrimidine-5-carboxaldehyde is used as a substrate in the synthesis of N-terminal surrogate in amino acid and peptide analogues.


Incompatible with strong oxidizing agents and strong acids. Store in cool place.

Literature References

Li, B.; Yue, Z.; Xiang, H.; Lv, L.; Song, S.; Miao, Z.; Yang, C. Catalyst-free synthesis of benzofuran-fused pyrido[4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions. RCS Adv. 2015, 4 (1), 358-364.

Schenone, S.; Radi, M.; Musumeci, F.; Brullo, C.; Botta, M. Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical Biology Studies. Chem. Rev. 2014, 114 (14), 7189-7238.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • 17574

    Bismuth(III) acetate, 99%
  • H50069

    3-Fluoropyridine-4-boronic acid pinacol ester, 97%
  • H66437

    1-Boc-2-trifluoromethyl-4-piperidone, 95%
  • L10329

    N-Acetyl-DL-alanine, 97+%
  • A14514

    4-(Trifluoromethyl)benzonitrile, 98%

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