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1-(2-Mesitylenesulfonyl)-3-Nitro-1H-1,2,4-Triazole is an efficient coupling reagent in the synthesis of oligonucleotides via phosphotriester approach.
Jörg Rademann.; Morten Grøtli.; Morten Meldal.; Klaus Bock. SPOCC:? A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase. zJ. Am. Chem. Soc. 1999, 121 (23),5459-5466.
Alexandra Papanikos.; Jörg Rademann.; Morten Meldal. α-Ketocarbonyl Peptides:? A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support.J. Am. Chem. Soc. 2001, 123 (10),2176-2181.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.