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74257-00-4 - 1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole, 99+% - H54792 - Alfa Aesar

H54792 1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole, 99+%

CAS Number
74257-00-4
Synonyms

Size Price ($) Quantity Availability
1g 82.50
5g 361.00
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1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole, 99+%

MDL
MFCD00009754

Chemical Properties

Formula
C11H12N4O4S
Formula Weight
296.30
Melting point
134-139°
Solubility
Soluble in Chloroform.

Applications

1-(2-Mesitylenesulfonyl)-3-Nitro-1H-1,2,4-Triazole is an efficient coupling reagent in the synthesis of oligonucleotides via phosphotriester approach.

Notes

Store at 4°C. Keep away from oxidizing agents.

Literature References

Jörg Rademann.; Morten Grøtli.; Morten Meldal.; Klaus Bock. SPOCC:? A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase. zJ. Am. Chem. Soc. 1999, 121 (23),5459-5466.

Alexandra Papanikos.; Jörg Rademann.; Morten Meldal. α-Ketocarbonyl Peptides:? A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support.J. Am. Chem. Soc. 2001, 123 (10),2176-2181.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4328921
Harmonized Tariff Code
2935.00
TSCA
No

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