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92921-24-9 - 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+% - Sulfo-SMCC - 4-(Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt - H54807 - Alfa Aesar

H54807 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%

CAS Number
92921-24-9
Synonyms
Sulfo-SMCC
4-(Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

Size Price ($) Quantity Availability
25mg 110.75
100mg 340.39
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3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%

MDL
MFCD00054978

Chemical Properties

Formula
C16H17N2NaO9S
Formula Weight
436.37
Solubility
Soluble in water (2.5 mg/ml) and dimethyl formamide.

Applications

3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Wolfgang J. Parak.; Daniele Gerion.; Daniela Zanchet.; Anke S. Woerz.; Teresa Pellegrino.; Christine Micheel.; Shara C. Williams.; Markus Seitz.; Richard E. Bruehl.; Zev Bryant.; Carlos Bustamante.; Carolyn R. Bertozzi.; A. Paul Alivisatos. Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots. Chem. Mater. 2002, 14 (5), 2113-2119.

Tsuyoshi Tanaka.; Tadashi Matsunaga. Fully Automated Chemiluminescence Immunoassay of Insulin Using Antibody-Protein A-Bacterial Magnetic Particle Complexes. Anal. Chem. 2000, 72 (15), 3518-3522.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2925.19
TSCA
No

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