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1810-71-5 - 6-Bromo-2-chloroquinoline, 96% - H54895 - Alfa Aesar

H54895 6-Bromo-2-chloroquinoline, 96%

CAS Number
1810-71-5
Synonyms

Size Price ($) Quantity Availability
250mg 25.60
1g 98.88
5g 395.52
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6-Bromo-2-chloroquinoline, 96%

MDL
MFCD04115272

Chemical Properties

Formula
C9H5BrClN
Formula Weight
242.50
Melting point
148-150°
Solubility
Soluble in Chloroform and Methanol

Applications

It is used as a pharmaceutical intermediate.

Notes

Store at room temperature with proper ventilation.

Literature References

Jessica A. Smith.; Rhiannon K. Jones.; Grant W. Booker.; Simon M. Pyke. Sequential and Selective Buchwald-Hartwig Amination Reactions for the Controlled Functionalization of 6-Bromo-2-chloroquinoline: Synthesis of Ligands for the Tec Src Homology 3 Domain. J. Org. Chem. 2008, 73 (22),8880-8892.

Eckhard Baston.; Anja Palusczak.; Rolf W. Hartmann. 6-Substituted 1H-quinolin-2-ones and 2-methoxy-quinolines: Synthesis and evaluation as inhibitors of steroid 5α reductases types 1 and 2. Eur. J. Med. Chem. 2000, 35 (10),931-940.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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