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H54910 Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, 98%

CAS Number
164298-23-1
Synonyms
N,N,N',N'-Tetramethylfluoroformamidiniun hexafluorophosphate
TFFH

Stock No. Size Price ($) Quantity Availability
H54910-03 1g 45.50
H54910-06 5g 173.00
H54910-14 25g 705.00
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Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, 98%

MDL
MFCD02684443

Chemical Properties

Formula
C5H12F7N2P
Formula Weight
264.12
Melting point
104-111°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate is used as a reagent for synthesis of cationic antimicrobial β-2,2-amino acid derivatives, philanthotoxin analogues for inhibition of the ionotropic glutamate receptor, small β-peptidomimetics for antimicrobials and hydrazone ligation to assemble multifunctional viral nanoparticles.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Terkel Hansen.; Dominik Ausbacher.; Gøril E Flaten.; Martina Havelkova.; Morten B Strom. Synthesis of cationic antimicrobial β(2,2)-amino acid derivatives with potential for oral administration. Journal of medicinal and pharmaceutical chemistry. 2011, 54 (3), 858-868.

Sidsel Frolund.; Angelo Bella.; Anders S Kristensen.; Hanne L Ziegler.; Matthias Witt.; Christian A Olsen.; Kristian Stromgaard.; Henrik Franzyk.; Jerzy W Jaroszewski. Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists. Journal of medicinal and pharmaceutical chemistry. 2010, 537 (20), 7441-7451.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2929.90
TSCA
No

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