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4-(Aminomethyl)indole is used as a reactant for preparation of dopamine receptor antagonists and for preparation of high-affinity ligands to α2δ subunit of voltage-gated calcium channels. It is used as a synthetic intermediate.
G. P. Zhikhareva.; S. A. Rabinovich.; E. V. Maksakovskaya.; N. R. Dadasheva.; M. N. Lebedeva.; N. P. Kozyreva.; Vu. Tkhi Tuet.; Din Van Shi.; A. M. Shcherbakov. Synthesis and antimalarial activity of 2-styryl-4-(δ-diethylamino-α-methylbutylamino)-7-chloroquinazolines. Pharmaceutical Chemistry Journal. 1990, 24 (10), 743-749.
M. V. Mezentseva.; I. S. Nikolaeva.; E. A. Golovanova.; A. N. Fomina. Synthesis and antiviral activity of 2-anilinomethyl derivatives of 5-hydroxyindole. Pharmaceutical Chemistry Journal. 1990, 24 (10), 749-751.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.