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459-59-6 - 4-Fluoro-N-methylaniline, 97% - H55105 - Alfa Aesar

H55105 4-Fluoro-N-methylaniline, 97%

CAS Number
459-59-6
Synonyms

Size Price ($) Quantity Availability
1g 26.00
5g 100.00
25g 423.00
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4-Fluoro-N-methylaniline, 97%

MDL
MFCD00017942
EINECS
207-294-1

Chemical Properties

Formula
C7FH8N
Formula Weight
125.15
Boiling Point
79°/11mm
Flash Point
76°(169°F)
Density
1.040
Refractive Index
1.5320

Applications

4-Fluoro-N-methylaniline is used as a model compound to study the in vivo and in vitro biotransformation of secondary aromatic amines.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents , acids, acid chloride, acid anhydride and chloroformates.

Literature References

James P. Driscoll.; Ignacio Aliagas.; Jennifer J. Harris, Jason S. Halladay.; Sheerin Khatib-Shahidi.; Alan Deese.; Nathaniel Segraves.; S. Cyrus Khojasteh-Bakht. Formation of a Quinoneimine Intermediate of 4-Fluoro-N-methylaniline by FMO1: Carbon Oxidation Plus Defluorination. Chem. Res. Toxico. 2011, 23 (5), 861-863.

M G Boersma.; N H Cnubben.; W J van Berkel.; M Blom.; J Vervoor.; I M Rietjens. Role of cytochromes P-450 and flavin-containing monooxygenase in the biotransformation of 4-fluoro-N-methylaniline. DMD. 1993, 21 (2), 218-230.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H302-H315-H318-H317-H335

Combustible liquid. Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause an allergic skin reaction. May cause respiratory irritation.

Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2921.42
TSCA
No

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