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Methyl methanesulfonate is a DNA adduct that adds methyl groups to Dan at 7-guanine, 3-guanine and 3-adenine.
D. Segerbäck.; C.J. Calleman.; L. Ehrenberg.; G. Löfroth.; S. Osterman-Golkar. Evaluation of genetic risks of alkylating agents IV. Quantitative determination of alkylated amino acids in haemoglobin as a measure of the dose after treatment of mice with methyl methanesulfonate. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 1978, 49 (1),71-82.
William F. Morgan.; James E. Cleaver. 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light .Mutation Research Letters. Mutation Research Letters, 104 (6),361-366.
Hazard Statements: H301-H315-H319-H341-H350-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause cancer. May cause respiratory irritation.
Precautionary Statements: P201-P261-P301+P310a-P305+P351+P338-P405-P501a
Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.