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66-27-3 - Methyl methanesulfonate, 99% - Methanesulfonic acid methyl ester - H55120 - Alfa Aesar

H55120 Methyl methanesulfonate, 99%

CAS Number
66-27-3
Synonyms
Methanesulfonic acid methyl ester

Size Price ($) Quantity Availability
5g 34.60
25g 118.00
100g 370.00
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Methyl methanesulfonate, 99%

MDL
MFCD00007557
EINECS
200-625-0

Chemical Properties

Formula
C2H6O3S
Formula Weight
110.13
Boiling Point
202-203°
Flash Point
104°(219°F)
Density
1.3
Refractive Index
1.4140
Solubility
Very soluble in water.

Applications

Methyl methanesulfonate is a DNA adduct that adds methyl groups to Dan at 7-guanine, 3-guanine and 3-adenine.

Notes

Store at room temperature with proper ventilation. Keep away from oxidizing agents.

Literature References

D. Segerbäck.; C.J. Calleman.; L. Ehrenberg.; G. Löfroth.; S. Osterman-Golkar. Evaluation of genetic risks of alkylating agents IV. Quantitative determination of alkylated amino acids in haemoglobin as a measure of the dose after treatment of mice with methyl methanesulfonate. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 1978, 49 (1),71-82.

William F. Morgan.; James E. Cleaver. 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light .Mutation Research Letters. Mutation Research Letters, 104 (6),361-366.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H341-H350-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause cancer. May cause respiratory irritation.

Precautionary Statements: P201-P261-P301+P310a-P305+P351+P338-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6097
Beilstein
1098586
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2905.11
TSCA
Yes
RTECS
PB2625000

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