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1780-31-0 - 2,4-Dichloro-5-methylpyrimidine, 98% - H55206 - Alfa Aesar

H55206 2,4-Dichloro-5-methylpyrimidine, 98%

CAS Number
1780-31-0
Synonyms

Size Price ($) Quantity Availability
250mg 15.20
1g 44.00
5g 162.00
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2,4-Dichloro-5-methylpyrimidine, 98%

MDL
MFCD00023197
EINECS
217-227-8

Chemical Properties

Formula
C5H4Cl2N2
Formula Weight
163.01
Melting point
26-28°
Boiling Point
108-109°/11mm
Flash Point
113°(235°F)
Density
1.39
Solubility
Soluble in chloroform, ether, ethyl acetate and toluene

Applications

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Henry C. Koppel.; Robert Henre Springer.; Roland K. Robins.; C. C. Cheng. Pyrimidines. V. Analogs of 2-(o-Chlorobenzylthio)-4-dimethylamino- 5-methylpyrimidine (Bayer DG-428)1. J. Org. Chem. 1962, 27, 91), 181-185.

Bryan W. Roberts.; Joseph B. Lambert.; John D. Roberts. Nitrogen-15 Magnetic Resonance Spectroscopy. VI. Pyrimidine Derivatives1,2. J. Am. Chem. Soc. 1965, 87, (23), 5439-5441.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2933.59
TSCA
Yes

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