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H55206 2,4-Dichloro-5-methylpyrimidine, 98%

CAS Number
1780-31-0
Synonyms

Stock No. Size Price ($) Quantity Availability
H55206-MD 250mg 14.70
H55206-03 1g 41.40
H55206-06 5g 152.00
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2,4-Dichloro-5-methylpyrimidine, 98%

MDL
MFCD00023197
EINECS
217-227-8

Chemical Properties

Formula
C5H4Cl2N2
Formula Weight
163.01
Melting point
26-28°
Boiling Point
108-109°/11mm
Flash Point
113°(235°F)
Density
1.39
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in chloroform, ether, ethyl acetate and toluene

Applications

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Henry C. Koppel.; Robert Henre Springer.; Roland K. Robins.; C. C. Cheng. Pyrimidines. V. Analogs of 2-(o-Chlorobenzylthio)-4-dimethylamino- 5-methylpyrimidine (Bayer DG-428)1. J. Org. Chem. 1962, 27, 91), 181-185.

Bryan W. Roberts.; Joseph B. Lambert.; John D. Roberts. Nitrogen-15 Magnetic Resonance Spectroscopy. VI. Pyrimidine Derivatives1,2. J. Am. Chem. Soc. 1965, 87, (23), 5439-5441.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2933.59
TSCA
Yes

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