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It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. It is a fine chemical intermediate.
Laurent Gomez.; Michael D. Hack.; Jiejun Wu.; John J.M. Wiener.; Hari Venkatesan.; Alejandro Santillán Jr.; Daniel J. Pippel.; Neelakandha Mani.; Brian J. Morrow.; S. Timothy Motley.; Karen Joy Shaw.; Ronald Wolin.; Cheryl A. Grice.; Todd K. Jones. Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis.Bioorg. Med. Chem. Lett. 2007, 17 (10), 2723-2727.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.