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3-Hydroxypiperidine hydrochloride is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
RC Fuson.; CL Zirkle. Ring enlargement by rearrangement of the 1, 2-aminochloroalkyl group; rearrangement of 1-ethyl-2-chloromethylpyrrolidine to 1-ethyl-3-chloropiperidine. J. Am. Chem. Soc. 194870 (8), 2760-2762.
MC Mitchell.; V Spikmans.; AJ de Mello. Microchip-based synthesis and analysis: control of multicomponent reaction products and intermediates. Analyst. 2001126 (1), 24-27.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.