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It function as a building block employed in the synthesis of HIV-1 protease inhibitors and is also employed in synthesizing (hydroxyethyl)urea peptidomimetrics and arylsulfonamides possessing anti-HIV activity. It is a Enantiomer S. Atazanavir intermediate.
Pierre L. Beaulieu.; Dominik Wernic. Preparation of Aminoalkyl Chlorohydrin Hydrochlorides:? Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors.J. Org. Chem. 1996, 61 (11),3635-3645 .