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98737-29-2 - (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98% - tert-Butyl [(S)-1-((S)-2-oxiranyl)-2-phenylethyl]carbamate - H56001 - Alfa Aesar

H56001 (2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98%

CAS Number
98737-29-2
Synonyms
tert-Butyl [(S)-1-((S)-2-oxiranyl)-2-phenylethyl]carbamate

Size Price ($) Quantity Availability
250mg 52.00
1g 150.00
5g 577.00
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(2S,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane, 98%

MDL
MFCD02258997
EINECS
425-420-5

Chemical Properties

Formula
C15H21NO3
Formula Weight
263.34
Melting point
125-127°
Solubility
Insoluble in water. Soluble in Chloroform, Dichloromethane and Ethyl Acetate.

Applications

It function as a building block employed in the synthesis of HIV-1 protease inhibitors and is also employed in synthesizing (hydroxyethyl)urea peptidomimetrics and arylsulfonamides possessing anti-HIV activity. It is a Enantiomer S. Atazanavir intermediate.

Notes

Store in a cool dry place. Incompatible with oxidizing agents. Keep container tightly closed.

Literature References

Pierre L. Beaulieu.; Dominik Wernic. Preparation of Aminoalkyl Chlorohydrin Hydrochlorides:? Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors.J. Org. Chem. 1996, 61 (11),3635-3645 .

GHS Hazard and Precautionary Statements

Hazard Statements: H400-H410

Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary Statements: P273-P391-P501a

Avoid release to the environment. Collect spillage. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2924.29
TSCA
No

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