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152305-23-2 - (S)-4-(4-Aminobenzyl)-2-oxazolidinone, 97% - H56017 - Alfa Aesar

H56017 (S)-4-(4-Aminobenzyl)-2-oxazolidinone, 97%

CAS Number
152305-23-2
Synonyms

Size Price ($) Quantity Availability
1g 12.64
5g 51.38
25g 219.20
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(S)-4-(4-Aminobenzyl)-2-oxazolidinone, 97%

MDL
MFCD03411476

Chemical Properties

Formula
C10H12N2O2
Formula Weight
192.22
Melting point
107-111°
Solubility
Soluble in dimethyl sulfoxide and methanol.

Applications

(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone is an intermediate of zolmitriptan (sc-220415) which acts as a novel inhibitor of the cytochrome P-450 enzyme aromatase.

Notes

Store at -20°C. Incompatible with oxidizing agents. Keep container tightly closed.

Literature References

Sabbir Ahmed.; Shaheen Adat.; Annabel Murrells.; Caroline P Owen.; Yonas Amanuel. Design, synthesis, and evaluation of 4-(4?-aminobenzyl)-2-oxazolidinones as novel inhibitors of the cytochrome P-450 enzyme aromatase.Bioorg. Chem. 2002, 30 (5),315-331 .

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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