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H56017 (S)-4-(4-Aminobenzyl)-2-oxazolidinone, 97%

CAS Number
152305-23-2
Synonyms

Stock No. Size Price ($) Quantity Availability
H56017-03 1g 14.90
H56017-06 5g 56.60
H56017-14 25g 233.00
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(S)-4-(4-Aminobenzyl)-2-oxazolidinone, 97%

MDL
MFCD03411476

Chemical Properties

Formula
C10H12N2O2
Formula Weight
192.22
Melting point
107-111°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in dimethyl sulfoxide and methanol.

Applications

(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone is an intermediate of zolmitriptan (sc-220415) which acts as a novel inhibitor of the cytochrome P-450 enzyme aromatase.

Notes

Store at -20°C. Incompatible with oxidizing agents. Keep container tightly closed.

Literature References

Sabbir Ahmed.; Shaheen Adat.; Annabel Murrells.; Caroline P Owen.; Yonas Amanuel. Design, synthesis, and evaluation of 4-(4?-aminobenzyl)-2-oxazolidinones as novel inhibitors of the cytochrome P-450 enzyme aromatase.Bioorg. Chem. 2002, 30 (5),315-331 .

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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