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1575-61-7 - 5-Chlorovaleroyl chloride, 98% - H56237 - Alfa Aesar

H56237 5-Chlorovaleroyl chloride, 98%

CAS Number
1575-61-7
Synonyms

Size Price ($) Quantity Availability
50g 215.00
100g 378.00
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5-Chlorovaleroyl chloride, 98%

MDL
MFCD00000758
EINECS
216-403-1

Chemical Properties

Formula
C5H8Cl2O
Formula Weight
155.02
Boiling Point
38-39°
Flash Point
91°(196°F)
Density
1.2
Refractive Index
1.464
Sensitivity
Moisture Sensitive
Solubility
Reacts with water.

Applications

5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.

Notes

Moisture sensitive. Incompatible with oxidizing agents, bases, alcohols, amines.

Literature References

Liya Tang.; Alexandre Kim.; Scott A. Miller.; David K. Lloyd. Development and validation of a specific and sensitive GC-FID method for the determination of impurities in 5-chlorovaleroyl chloride.J. Pharm. Biomed. Anal. 2010, 53 (3), 309-314.

T. N. Kas’yanova.; A. D. Smolenkov.; A. V. Pirogov.; O. A. Shpigun. Effect of the acylating agent on the selectivity of anion-exchange resins and separation efficiency. Moscow University Chemistry Bulletin. 2007, 62 (5), 286-289.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H302-H227

Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed. Combustible liquid.

Precautionary Statements: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1745182
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
No
RTECS
YV9108000

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