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H56237 5-Chlorovaleroyl chloride, 98%

CAS Number
1575-61-7
Synonyms

Stock No. Size Price ($) Quantity Availability
H56237-18 50g 220.00
H56237-22 100g 386.00
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5-Chlorovaleroyl chloride, 98%

MDL
MFCD00000758
EINECS
216-403-1

Chemical Properties

Formula
C5H8Cl2O
Formula Weight
155.02
Boiling Point
38-39°
Flash Point
91°(196°F)
Density
1.2
Refractive Index
1.464
Storage & Sensitivity
Moisture Sensitive. Ambient temperatures.
Solubility
Reacts with water.

Applications

5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.

Notes

Moisture sensitive. Incompatible with oxidizing agents, bases, alcohols, amines.

Literature References

Liya Tang.; Alexandre Kim.; Scott A. Miller.; David K. Lloyd. Development and validation of a specific and sensitive GC-FID method for the determination of impurities in 5-chlorovaleroyl chloride.J. Pharm. Biomed. Anal. 2010, 53 (3), 309-314.

T. N. Kas’yanova.; A. D. Smolenkov.; A. V. Pirogov.; O. A. Shpigun. Effect of the acylating agent on the selectivity of anion-exchange resins and separation efficiency. Moscow University Chemistry Bulletin. 2007, 62 (5), 286-289.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H302-H314

Combustible liquid. Harmful if swallowed. Causes severe skin burns and eye damage.

Precautionary Statements: P210-P235-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1745182
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
No
RTECS
YV9108000

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