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H57501 N-(3-Bromophenyl)-3-(trifluoromethyl)benzamide, 97%

CAS Number
Synonyms

Stock No. Size Price ($) Quantity Availability
H57501-MD 250mg 137.00
H57501-03 1g 438.00
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N-(3-Bromophenyl)-3-(trifluoromethyl)benzamide, 97%

Chemical Properties

Formula
C14H9BrF3NO
Formula Weight
344.13
Storage & Sensitivity
Ambient temperatures.

Applications

The derivatives of this compound were identified as highly potent Bcr-Abl kinase inhibitors that is used to treat chronic myeloid leukemia.

Notes

Store in a cool ventilated place. Avoid strong oxidizing materials. Hygroscopic.

Literature References

Tomas de Paulis.; Kamondanai Hemstapat.; Yelin Chen.; Yongqin Zhang.; Samir Saleh.; David Tomas de Paulis.; Kamondanai Hemstapat.; Yelin Chen.; Yongqin Zhang.; Samir Saleh.; David. Substituent Effects of N-(1,3-Diphenyl-1H-pyrazol-5-yl)benzamides on Positive Allosteric Modulation of the Metabotropic Glutamate-5 Receptor in Rat Cortical Astrocytes.J. Med. Chem. 2006, 49 (11),3332-3344.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2924.29

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