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H57808 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%

CAS Number
349085-82-1
Synonyms
N-Mesityl-4-methoxybenzenesulfonamide

Stock No. Size Price ($) Quantity Availability
H57808-MD 250mg 84.00
H57808-03 1g 267.00
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4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%

MDL
MFCD02007969

Chemical Properties

Formula
C16H19NO3S
Formula Weight
305.39
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol.

Applications

4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. It enhances glucose-stimulated insulin secretion in MIN6 cells. It induces intracellular calcium accumulation in U2OS cells; this activity is inhibited by AH 7614.

Notes

Store away from oxidizing agents. Store in a dry, cool conditions in a well sealed containers.

Literature References

Da Young Oh; Evelyn Walenta. Omega-3 Fatty Acids and FFAR4. Frontiers in Endocrinology. 2014, 5 115.

Céline Martin; Patricia Passilly-Degrace; Michaël Chevrot; Déborah Ancel; Steven M Sparks; Daniel J Drucker; Philippe Besnard. Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity. Journal of Lipid Research. 2012, 53 (11), 2256-2265.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
23102756
Harmonized Tariff Code
2935.90
TSCA
No

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