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15166-68-4 - 3-Hydroxy-2-pyrrolidinone, 95% - H57961 - Alfa Aesar

H57961 3-Hydroxy-2-pyrrolidinone, 95%

CAS Number
15166-68-4
Synonyms

Size Price ($) Quantity Availability
250mg 35.70
1g 128.00
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3-Hydroxy-2-pyrrolidinone, 95%

MDL
MFCD09751256

Chemical Properties

Formula
C4H7NO2
Formula Weight
101.11
Melting point
102-107°
Sensitivity
Moisture Sensitive

Applications

3-Hydroxy-2-pyrrolidinone is used as a potent inhibitor of CDK2/cyclin A. It is also used as pharmaceutical intermediates.

Notes

Moisture Sensitive. Store away from moisture and oxidizing agents. Store under dry inert gas. Incompatible with heat, oxidizing agents and moisture.

Literature References

Marcella Nesi; Daniela Borghi; Maria Gabriella Brasca; Francesco Fiorentini; Paolo Pevarello. A practical synthesis of the major 3-hydroxy-2-pyrrolidinone metabolite of a potent CDK2/cyclin A inhibitor. Bioorganic & Medicinal Chemistry Letters.2006, 16 3205-3208.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H319

Harmful if swallowed. Causes serious eye irritation.

Precautionary Statements: P280i-P264-P305+P351+P338-P301+P312a-P337+P313-P501a

Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. If eye irritation persists: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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