Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

126403-68-7 - Cyclopropylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles - H58008 - Alfa Aesar

H58008 Cyclopropylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles

CAS Number
126403-68-7
Synonyms

Size Price ($) Quantity Availability
50ml 252.90
Add to Cart Add to Quote Request View Item

Cyclopropylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles

MDL
MFCD08741505

Chemical Properties

Formula
C3H5BrZn
Formula Weight
186.36
Density
0.969
Sensitivity
Air Sensitive
Solubility
Miscible with tetrahydrofuran.

Applications

Cyclopropylzinc bromide acts as an active nucleophile in palladium-catalyzed cross-coupling of heteroaryl halides.

Notes

Heat and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with acids, acid chlorides, oxidizing agents, chloroformates, alcohols, peroxides and strong bases.

Literature References

Coleridge, B. M.; Bello, C. S.; Leitner, A. General and user-friendly protocol for the synthesis of functionalized aryl- and heteroaryl-cyclopropanes by Negishi cross-coupling reactions. Tetrahedron Lett. 2009, 50 (31), 4475-4477.

Shu, C.; Sidhu, K.; Zhang, L.; Wang, X. J.; Krishnamurthy, D.; Senanayake, C. H. Palladium-Catalyzed Cross-Coupling of Cyclopropylmagnesium Bromide with Aryl Bromides Mediated by Zinc Halide Additives. J. Org. Chem. 2010, 75 (19), 6677-6680.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H261-H314-H351-H335

Highly flammable liquid and vapour. In contact with water releases flammable gas. Causes severe skin burns and eye damage. Suspected of causing cancer. May cause respiratory irritation.

Precautionary Statements: P210-P231+P232-P260-P201-P261-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Handle under inert gas. Protect from moisture. Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
4.3
Packing Group
II
Harmonized Tariff Code
2931.90
TSCA
No

Recommended

  • H58119

    n-Propylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles
  • H58145

    Isobutylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles
  • H58536

    Isopropylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware