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79642-50-5 - Disuccinimidyl glutarate, 97% - Di(N-succinimidyl) glutarate - DSG - H58208 - Alfa Aesar

H58208 Disuccinimidyl glutarate, 97%

CAS Number
79642-50-5
Synonyms
Di(N-succinimidyl) glutarate
DSG

Size Price ($) Quantity Availability
100mg 86.50
500mg 343.00
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Disuccinimidyl glutarate, 97%

MDL
MFCD00153597

Chemical Properties

Formula
C13H14N2O8
Formula Weight
326.26
Sensitivity
Moisture Sensitive
Solubility
Soluble in dimethylsulfoxide and dimethylformamide. Partially soluble in water.

Applications

Disuccinimidyl glutarate is used as a membrane-soluble, amine-reactive N-hydroxysuccinamide ester-based homobifunctional crosslinking reagent. It is a homobifunctionla cross-linking reagent, for ex. isolation of the insulin receptor.

Notes

Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Morioka, T.; Loik, N. D.; Hipolito, C. J.; Goto, Y.; Suga, H. Selection-based discovery of macrocyclic peptides for the next generation therapeutics. Curr. Opin. Chem. Biol. 2015, 26, 34-41.

Smaldone, G.; Diana, D.; Pollegioni, L.; Di Gaetano, S.; Fattorusso, R.; Pedone, E. Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes. FEBS Lett. 2015, 589 (7), 798-804.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
8575145
Harmonized Tariff Code
2928.00
TSCA
No

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