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74844-91-0 - N-Boc-trans-4-hydroxy-L-proline methyl ester, 97% - H59027 - Alfa Aesar

H59027 N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%

CAS Number
74844-91-0
Synonyms

Size Price ($) Quantity Availability
1g 26.70
5g 93.30
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N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%

MDL
MFCD00076981

Chemical Properties

Formula
C11H19NO5
Formula Weight
245.28
Melting point
92-96°
Solubility
Soluble in chloroform, dichloromethane and ethyl acetate.

Applications

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Richard J. Freer; Alan R. Day; Natesa Muthukumaraswamy; Delia Pinon; Arthur Wu; Henry J. Showell; Elmer L. Becker. Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils. Biochemistry,1982, 21(2), 257-263.

Higgins, J., et al. N-Terminus Urea-Substituted Chemotactic Peptides:? New Potent Agonists and Antagonists toward the Neutrophil fMLF Receptor. J. Med. Chem,1996, 39(5), 1013-1015.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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