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71989-26-9 - Nepsilon-Boc-Nalpha-Fmoc-L-lysine, 98% - Fmoc-Lys(Boc)-OH - H59182 - Alfa Aesar

H59182 Nepsilon-Boc-Nalpha-Fmoc-L-lysine, 98%

CAS Number
71989-26-9
Synonyms
Fmoc-Lys(Boc)-OH

Size Price ($) Quantity Availability
5g 40.89
25g 139.00
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Nepsilon-Boc-Nalpha-Fmoc-L-lysine, 98%

MDL
MFCD00037138
EINECS
276-256-4

Chemical Properties

Formula
C26H32N2O6
Formula Weight
468.54
Melting point
130-135°
Solubility
Slightly soluble in water.

Applications

It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.

Notes

Refrigerate. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Xiaoyuan Chen; Carmen Plasencia; Yingping Hou; and Nouri Neamati. Synthesis and Biological Evaluation of Dimeric RGD Peptide-Paclitaxel Conjugate as a Model for Integrin-Targeted Drug Delivery. J. Med. Chem,2005,48 (4), 1098-1106.

Dijkgraaf, I., et al. Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes. Org. Biomol. Chem,2007, 5(6), 935-944.

Other References

Beilstein
4217767
Harmonized Tariff Code
2924.29
TSCA
No

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