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1001-26-9 - Ethyl 3-ethoxyacrylate, 98% - Ethyl 3-ethoxy-2-propenoate - H59187 - Alfa Aesar

H59187 Ethyl 3-ethoxyacrylate, 98%

CAS Number
1001-26-9
Synonyms
Ethyl 3-ethoxy-2-propenoate

Ethyl 3-ethoxyacrylate, 98%

MDL
MFCD00009863

Chemical Properties

Formula
C7H12O3
Formula Weight
144.17
Boiling Point
195-196°
Flash Point
76°(169°F)
Density
0.998
Refractive Index
1.4465
Solubility
Slightly soluble in water.

Applications

Used in the preparation of N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-5-yl)phenyl]-N-ethylacetamide.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Bertz SH, et al. New preparations of ethyl 3, 3-diethoxypropionate and ethoxycarbonylmalondialdehyde. Copper (I) catalyzed acetal formation from a conjugated triple bond. J. Org. Chem,1982,47(11), 2216-17.

Jagusch, C., et al. Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure. Bioorganic & Medicinal Chemistry,2008, 16(4), 1992-2010.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319-H335

Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1721612
Hazard Class
9
Harmonized Tariff Code
2918.99
TSCA
No

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