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H59231 Ethyl 4,6-dichloroquinoline-3-carboxylate, 97%

CAS Number
21168-41-2
Synonyms
4,6-Dichloroquinoline-3-carboxylic acid ethyl ester

Stock No. Size Price ($) Quantity Availability
H59231-MD 250mg 35.80
H59231-03 1g 114.00
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Ethyl 4,6-dichloroquinoline-3-carboxylate, 97%

MDL
MFCD00173348

Chemical Properties

Formula
C12H9Cl2NO2
Formula Weight
270.11
Storage & Sensitivity
Ambient temperatures.

Applications

It is used as a pharmaceutical intermediate.

Notes

Store at room temperature. Keep away from oxidizing agents.

Literature References

Qingsong Liu.;Jae Won Chang.; Jinhua Wang.; Seong A. Kang.; Carson C. Thoreen.; Andrew Markhard.; Wooyoung Hur.; Jianming Zhang.; Taebo Sim.; David M. Sabatini.; Nathanael S. Gray. Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer. J. Med. Chem. 2010, 53 (19), 7146-7155.

Charles J. Paget.; Charles W. Ashbrook.; Robert Louis Stone.; Heterocyclic substituted ureas. III. Immunosuppressive and antiviral (2-pyrimidinyl)ureas. J. Med. Chem. 1969, 12 (6),1097-1098.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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