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206257-39-8 - Ethyl 6-bromo-4-chloroquinoline-3-carboxylate, 97% - 6-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester - H59301 - Alfa Aesar

H59301 Ethyl 6-bromo-4-chloroquinoline-3-carboxylate, 97%

CAS Number
206257-39-8
Synonyms
6-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester

Size Price ($) Quantity Availability
250mg 22.86
1g 98.13
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Ethyl 6-bromo-4-chloroquinoline-3-carboxylate, 97%

MDL
MFCD00173367

Chemical Properties

Formula
C12H9BrClNO2
Formula Weight
314.57
Solubility
Immiscible in water.

Applications

Ethyl 6-bromo-4-chloroquinoline-3-carboxylate is used as pharmaceutical intermediates

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Qingsong Liu.; Jinhua Wang.; Seong A. Kang.; Carson C. Thoreen.; Wooyoung Hur.; Tausif Ahmed.; David M. Sabatini.; Nathanael S. Gray. Discovery of 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a Potent, Selective, and Orally Available Mammalian Target of Rapamycin (mTOR) Inhibitor for Treatment of Cancer. J. Med. Chem. 2011, 54, (5), 1473-1480.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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