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59016-56-7 - 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98% - CDAP - H59334 - Alfa Aesar

H59334 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98%

CAS Number
59016-56-7
Synonyms
CDAP

Size Price ($) Quantity Availability
100mg 72.72
500mg 253.80
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1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98%

MDL
MFCD00011998

Chemical Properties

Formula
C8H10BF4N3
Formula Weight
234.99
Melting point
196-200°
Solubility
Soluble in water, and acetonitrile.

Applications

1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.

Notes

Store at room temperature. Keep away from oxidizing agents and heats.

Literature References

Joachim Kohn.; Meir Wilchek. 1-Cyano-4-dimethylamino pyridinium tetrafluoroborate as a cyanylating agent for the covalent attachment of ligand to polysaccharide resins. FEBS Lett. 1983, 154 (1), 209-210.

Andrew Lees.; Brett L. Nelson.; James J. Mond. Activation of soluble polysaccharides with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate for use in protein—polysaccharide conjugate vaccines and immunological reagents. Vaccine. 1996, 14 (3),190-198.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H332-H315-H319-H335

Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
5685616
Harmonized Tariff Code
2933.39
TSCA
No

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