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H59334 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98%

CAS Number
59016-56-7
Synonyms
CDAP

Stock No. Size Price ($) Quantity Availability
H59334-MC 100mg 82.10
H59334-ME 500mg 285.00
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1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98%

MDL
MFCD00011998

Chemical Properties

Formula
C8H10BF4N3
Formula Weight
234.99
Melting point
196-200°
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in water, and acetonitrile.

Applications

1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.

Notes

Store at room temperature. Keep away from oxidizing agents and heats.

Literature References

Joachim Kohn.; Meir Wilchek. 1-Cyano-4-dimethylamino pyridinium tetrafluoroborate as a cyanylating agent for the covalent attachment of ligand to polysaccharide resins. FEBS Lett. 1983, 154 (1), 209-210.

Andrew Lees.; Brett L. Nelson.; James J. Mond. Activation of soluble polysaccharides with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate for use in protein—polysaccharide conjugate vaccines and immunological reagents. Vaccine. 1996, 14 (3),190-198.

GHS Hazard and Precautionary Statements

Hazard Statements: H302+H312+H332-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
5685616
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2933.39
TSCA
No

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