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It is used as an intermediate in organic syntheses
A. El Akkaoui.; J. Koubachi.; S. El Kazzoulia.; S. Berteina-Raboin.; A. Mouaddib.; G. Guillaumeta. Efficient and regioselective functionalization of imidazo[1,2-b]pyridazines via palladium-catalyzed cross-coupling reaction and SNAr.Tetrahedron Lett. 2008, 49 (15), 2472-2475.
Ken-ichi Kusakabe.; Nobuyuki Ide.; Yataro Daigo.; Takeshi Itoh.; Takahiko Yamamoto.; Hiroshi Hashizume.; Kohei Nozu.; Hiroshi Yoshida.; Genta Tadanp.; Sachie Tagashira.; Kenichi Higashino.; Yousuke Okano.; Yuji Sato.; Makiko Inoue.; Motofumi Iguchi.; Takayuki Kanazawa.; Yukichi Ishioka.; Keiji Dohi.; Yasuto Kido.; Shingo Sakamoto.; Shigeru Ando.; Masahiro Maeda.; Masayo Higaki.; Yoshiyasu Baba.; Yusuke Nakamura. Discovery of Imidazo[1,2-b]pyridazine Derivatives: Selective and Orally Available Mps1 (TTK) Kinase Inhibitors Exhibiting Remarkable Antiproliferative Activity. J. Med. Chem. 2015, 58 (4),1760-1775.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant